Medical waste rules in Illinois

Illinois calls it potentially infectious medical waste (PIMW). The Illinois EPA regulates it under Title XV of the Environmental Protection Act and 35 Ill. Adm. Code Parts 1420 to 1422: PIMW is waste generated in the diagnosis, treatment or immunization of humans or animals, in related research, or in producing or testing biologicals (35 Ill. Adm. Code 1420.102).

  • Packaging: PIMW leaving the site goes in containers that are rigid, leak-resistant, impervious to moisture, strong enough not to tear or burst in normal handling, and sealed for transport; sharps containers must also be puncture-resistant.
  • Labeling: two opposite sides of each package show the word BIOHAZARD, the word Sharps where applicable, and the international biohazard symbol, readable from five feet, plus a water-resistant label with the generator's name, address and phone number in indelible ink.
  • Storage: keep PIMW in a non-putrescent state, refrigerating when necessary. The limits are 72 hours unless the package surface is held at or below 45°F, and 30 days regardless of temperature.
  • Transport: only a hauler with an Illinois EPA PIMW permit may carry PIMW, and only to a permitted transfer, storage or treatment facility.
  • Manifests: the hauler initiates a PIMW manifest for each shipment and leaves the generator a copy. A manifest is not required when less than 50 pounds is carried non-commercially at one time or when the U.S. Postal Service is the carrier (35 Ill. Adm. Code 1420.105(e)). Facilities keep manifest copies for at least three years.
  • Treatment: untreated PIMW may not go to a landfill. Treatment must eliminate the infectious potential of the waste and sharps must be rendered unrecognizable or properly packaged before disposal (35 Ill. Adm. Code 1422).

Source: Illinois EPA, Potentially Infectious Medical Waste regulations.

Reviewed September 2026.

This summary is general information, not legal advice. Requirements change; we confirm what applies to your facility during onboarding.Regulations by state

Services in Illinois

  1. Regulated Medical Waste and Biohazard Waste DisposalScheduled or on-call pickup of regulated medical waste, also called biohazard or red bag waste, from healthcare facilities: compliant containers, permitted transport and a manifest for every collection.Red bag, cardboard box
  2. Sharps Waste DisposalSharps container supply, exchange and disposal for practices of every size, from a single dental office to a hospital network.Red sharps container
  3. Pharmaceutical Waste DisposalCompliant collection and disposal of expired, unused and partially used non-hazardous pharmaceuticals, with the right stream for each drug.Blue container
  4. Trace Chemotherapy Waste DisposalYellow-container collection for trace chemotherapy waste from oncology, infusion and specialty practices.Yellow container
  5. RCRA Hazardous Pharmaceutical WasteBlack-container programs for RCRA-listed and characteristic hazardous pharmaceutical waste, with generator-status guidance and cradle-to-grave documentation.Black container
  6. Pathological Waste DisposalDedicated, labeled collection for tissues, organs and surgical specimens from surgery centers, labs, dermatology practices and veterinary clinics.Red bag, pathology label

Facilities we serve in Illinois

All facility types

Illinois service questions

Do you serve every part of Illinois?

We coordinate service through a network of qualified providers, and coverage in Illinois is confirmed address by address. Tell us your address and operations confirms whether a route is available before anything is promised.

Which rules apply to medical waste in Illinois?

Medical waste is regulated at the state level, alongside the federal OSHA, DOT and EPA rules that apply everywhere. The summary above covers the Illinois requirements that most affect small and mid-size generators. See our regulations guide for the federal picture and links to every state.

What waste streams can you pick up in Illinois?

Regulated (biohazardous) medical waste, sharps, pharmaceutical waste, trace chemotherapy waste, RCRA hazardous pharmaceutical waste and pathological waste, subject to verification of each stream at onboarding.

We are under contract. Can we still talk?

Of course. Most facilities are. Share your renewal date and we will follow up before it, so you can compare options without being rushed.

Medical waste pickup in Illinois

Send us your facility list and current schedule. We reply with a clear quote and a start date operations has confirmed.