Medical waste rules in Maryland

Maryland calls it special medical waste and splits it between two agencies. The Maryland Department of Health defines the waste and the acceptable treatment methods in COMAR 10.06.06; the Maryland Department of the Environment (MDE) regulates generators, shipping papers and haulers in COMAR 26.13.11 to 26.13.13. The dividing line is 50 pounds a month.

  • What counts (COMAR 10.06.06.02, 26.13.11.02): liquid or semi-liquid blood and other potentially infectious material, items that would release it if compressed or that carry dried blood capable of flaking off, pathological and microbiological waste, contaminated sharps and anatomical material. Household waste, animal waste without a known zoonotic disease and incinerator ash are excluded (26.13.11.03).
  • The 50-pound line (COMAR 26.13.11.03 B to D): a generator producing less than 50 pounds of special medical waste in a calendar month is excluded from the MDE generator and transporter rules, provided it still makes the waste determination and packages, marks and labels to US DOT standards and treats as required; accumulating more than 50 pounds brings the waste back under the rules. MDE says notification is required at 50 pounds or more in a month or more than 50 pounds on site at any time.
  • Identification numbers and shipping papers (COMAR 26.13.12.03, 26.13.12.04): a regulated generator may not treat, store, transport or offer special medical waste for transport without a Maryland identification number from MDE, may only hand waste to a transporter that also holds one, and prepares a shipping paper to 49 CFR 172.200 to 172.204 for every off-site shipment.
  • Packaging (COMAR 26.13.12.05): before waste leaves, the generator classifies it under the US DOT hazardous materials rules (usually Regulated medical waste, n.o.s. or Infectious substances, affecting humans), packages it to 49 CFR Part 173 and marks and labels it to Part 172. Sharps may not go to a landfill unless incinerated, or sterilised and then mechanically destroyed. Handling on site follows OSHA 29 CFR 1910.1030 (COMAR 10.06.06.03).
  • Treatment (COMAR 10.06.06.04 to .07): autoclaving, chemical disinfection, incineration, disinfection, mechanical destruction after decontamination or an approved alternative; sharps by encapsulation, incineration or mechanical destruction after decontamination. Liquid waste may go to the sanitary sewer where local rules allow.
  • Haulers (COMAR 26.13.13.01): a special medical waste hauler holds an MDE state identification number and a per-vehicle certificate backed by a bond of at least $10,000, an annual fee of up to $50 per vehicle and a safety inspection; vehicles are leakproof, non-compacting and fully enclosed, and a loaded vehicle may not stop for more than 72 hours at a stretch or five days in total. Generators keep annual and exception reports for three years (COMAR 26.13.12.06); the state rules set no day limit for on-site storage.

Source: Maryland Department of Health, Special Medical Waste (COMAR 10.06.06, with MDE transport rules at COMAR 26.13.11 to 26.13.13).

Reviewed September 2026.

This summary is general information, not legal advice. Requirements change; we confirm what applies to your facility during onboarding.Regulations by state

Services in Maryland

  1. Regulated Medical Waste and Biohazard Waste DisposalScheduled or on-call pickup of regulated medical waste, also called biohazard or red bag waste, from healthcare facilities: compliant containers, permitted transport and a manifest for every collection.Red bag, cardboard box
  2. Sharps Waste DisposalSharps container supply, exchange and disposal for practices of every size, from a single dental office to a hospital network.Red sharps container
  3. Pharmaceutical Waste DisposalCompliant collection and disposal of expired, unused and partially used non-hazardous pharmaceuticals, with the right stream for each drug.Blue container
  4. Trace Chemotherapy Waste DisposalYellow-container collection for trace chemotherapy waste from oncology, infusion and specialty practices.Yellow container
  5. RCRA Hazardous Pharmaceutical WasteBlack-container programs for RCRA-listed and characteristic hazardous pharmaceutical waste, with generator-status guidance and cradle-to-grave documentation.Black container
  6. Pathological Waste DisposalDedicated, labeled collection for tissues, organs and surgical specimens from surgery centers, labs, dermatology practices and veterinary clinics.Red bag, pathology label

Facilities we serve in Maryland

All facility types

Maryland service questions

Do you serve every part of Maryland?

We coordinate service through a network of qualified providers, and coverage in Maryland is confirmed address by address. Tell us your address and operations confirms whether a route is available before anything is promised.

Which rules apply to medical waste in Maryland?

Medical waste is regulated at the state level, alongside the federal OSHA, DOT and EPA rules that apply everywhere. The summary above covers the Maryland requirements that most affect small and mid-size generators. See our regulations guide for the federal picture and links to every state.

What waste streams can you pick up in Maryland?

Regulated (biohazardous) medical waste, sharps, pharmaceutical waste, trace chemotherapy waste, RCRA hazardous pharmaceutical waste and pathological waste, subject to verification of each stream at onboarding.

We are under contract. Can we still talk?

Of course. Most facilities are. Share your renewal date and we will follow up before it, so you can compare options without being rushed.

Medical waste pickup in Maryland

Send us your facility list and current schedule. We reply with a clear quote and a start date operations has confirmed.